Oct 24, 2019
Skin appearance is a sign of internal health, and patients who
have appropriate vitamin levels naturally have healthier skin. Dr.
Vincent DeLeo talks with Dr. Gary Goldenberg about
the data on vitamins and supplements that have been shown to
improve the skin’s appearance and health. Dr. Goldenberg discusses
the controversies surrounding the quality of products and the need
for dermatologists to remain up-to-date on products their patients
may be taking already. “A discussion of nutrition and supplements
really is a part of any dermatologic evaluation, just like skin
care should be part of every dermatologic evaluation,” advises Dr.
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We bring you the latest in dermatology news and
1. Rituximab bests mycophenolate in pemphigus
Rituximab showed a superior overall benefit/risk profile,
compared with mycophenolate mofetil.
2. Once-daily oral JAK inhibitor for atopic dermatitis
effective in phase 3 study
Abrocitinib may have taken a step closer to becoming the first
once-daily oral Janus kinase 1 inhibitor to be approved for atopic
3. Online resources influencing cosmetic treatment
Rate and review websites affect almost 70% of consumers seeking
providers for cosmetic procedures.
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Things you will learn in this episode:
- Patients who have good nutrition also will have appropriate
vitamin levels, which contributes to having healthier skin. Dr.
Goldberg explains, “Patients who have really low vitamin D levels
will not be as healthy and cannot have as healthy skin as those who
have more normal vitamin D levels.”
- Studies have shown that internal vitamin C levels reduce
oxidative stress and help with the appearance of fine wrinkles,
lines, and pigmentation. “As far as topical vitamin C goes, I think
that there [are] good data showing that vitamin C improves the
appearance of skin. But the issue with vitamin C is the delivery of
the product into the skin,” advises Dr. Goldenberg. Vitamin E is
one of the best antioxidants, according to Dr. Goldenberg, and is
especially helpful for UV-induced oxidative stress.
- Carotenoids, which are derived from vitamin A, can help reduce
oxidative stress associated with UV-induced radiation and
UV-induced erythema. “We also know that carotenoids actually
improve UV-damaged cells such as for patients with a history of
skin cancer,” says Dr. Goldenberg.
- Studies have reported that oral collagen supplements can
improve skin health and appearance. However, Dr. Goldenberg remains
skeptical: “It’s still unclear to me if the improvement is due to
the actual collagen or to the water that patients may be taking the
collagen in, especially if it’s a powder.” Hydration is very
important for skin appearance and health, he adds.
- Imedeen supplementation has some data that show antioxidant
properties. Although it’s too early to say that Imedeen is
completely effective, studies report efficacy for skin appearance
- In terms of side effects associated with vitamins and
supplements, Dr. Goldenberg advises that not all supplements have
the same quality, and patients should consult a nutritionist for
advice on which vitamins and supplements are needed. “Not all
supplements are going to have the same quality. So if you’re going
with the least expensive ones, they may have the least absorption.
Now the most expensive ones may have the prettiest packaging and
not necessarily be the highest quality of the vitamin.”
- Dermatologists, as skin experts, need to be aware of the data
on vitamins and supplements because diet or nutrition is a common
question among patients. For example, patients with acne,
psoriasis, eczema, or rosacea may inquire if their condition is
caused by a supplement they take or by the lack of supplements.
“[We] have to be aware of all of the positive and negative data
that’s out there and what I call ‘pseudo’ data, which is blogging,
Instagram influencers, etc.,” Dr. Goldenberg says.
Guests: Gary Goldenberg, MD
(Icahn School of Medicine at Mount Sinai, New York, and Goldenberg
Dermatology, PC, New York)
Show notes by: Jason Orszt, Melissa Sears,
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Gary Goldenberg on Twitter: @Goldenberg_Derm